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prostate-specific antigen
noun
pros·tate-spe·cif·ic antigen
: a protease secreted by epithelial cells of the prostate gland that is used in the diagnosis of prostate cancer since its concentration in blood serum tends to be proportional to the clinical stage of the disease
—abbreviation PSA
Examples of prostate-specific antigen in a Sentence
Recent Examples on the Web
Some people do not experience symptoms, so regular screening with prostate-specific antigen (PSA) tests and digital rectal exams (DRE) are important for early detection.
—Brandi Jones, Msn-Ed, Health, 5 Sep. 2024
Separately, right before the pandemic hit in February 2020, my general practitioner began noticing my prostate-specific antigen (PSA) levels were increasing.
—Rachel Chang, Travel + Leisure, 4 Sep. 2024
And huge gains made in prostate cancer death rates from the mid-1990s through the early 2000s – a result of the emergence of prostate-specific antigen (PSA) testing – appear to have leveled off since about 2012.
—Andre Mouchard, Orange County Register, 28 July 2024
Though blood tests known as prostate-specific antigen (PSA) tests are now the standard for screening, many men still associate prostate cancer exams with rectal exams.
—Robin Cole, Fortune, 12 Apr. 2024
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Word History
First Known Use
1979, in the meaning defined above
Time Traveler
The first known use of prostate-specific antigen was
in 1979
Dictionary Entries Near prostate-specific antigen
Cite this Entry
“Prostate-specific antigen.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/prostate-specific%20antigen. Accessed 2 Dec. 2024.
Medical Definition
prostate-specific antigen
noun
: a protease that is secreted by the epithelial cells of the prostate and is used in the diagnosis of prostate cancer since its concentration in the blood serum tends to be proportional to the clinical stage of the disease
—abbreviation PSA
More from Merriam-Webster on prostate-specific antigen
Britannica.com: Encyclopedia article about prostate-specific antigen
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